I have done some testing with SSDs on both ends. With hot transfers, when transferring using the 100Mb pipe I get around 105Mb, so very little optimization. Going the other way on the 20Mb pipe I get around 55Mb so almost 300% optimization.
(These numbers are calculated simply by dividing transfer time by the file size of a test (uncompressed) Revit file.)
Im not sure what is limiting the 100Mb pipe, but it almost seems like it bursts to 200% then tapers off quickly, but that may be windows reporting transfer speeds inconsistently. Again this is with an E3-1245 processor sending on the fast pipe and a X5450 receiving, so pretty fast processing on both ends. The "top" interface doesnt show an IO or CPU bottleneck, but I am only running a single MX100 128Gb on both ends... for these speeds, Riverbed and Silverpeak recommend 4-6 SSD drives!
BTW, ESXi introduces almost no IO overhead... maybe 3-5% at most from testing I have done.
That said, I have ordered one of these:
http://ark.intel.com/products/67008/Intel-SSD-910-Series-400GB-12-Height-PCIe-2_0-25nm-MLCIf that doesnt eliminate IO as a possible bottleneck, I dont know what will.

I will report back after installing on the new SSD and testing transfer speeds.